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ETV6-NTRK3 gene fusion : ウィキペディア英語版 | ETV6-NTRK3 gene fusion ETV6-NTRK3 gene fusion is the translocation of genetic material between chromosomes 12 and 15 (t(12;15)). This creates a new gene in which the 5' region of ETV6 is fused to the 3' region of NTRK3. The resulting transcript encodes and chimeric oncoprotein consisting of the helix-loop-helix (HLH) protein dimerization domain of ETV6 fused to the protein tyrosine kinase (PTK) domain of NTRK3. The ETV6-NTRK3 gene fusion was originally identified in congenital fibrosarcoma 〔 but has since been identified in secretory breast carcinoma. == References == 〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「ETV6-NTRK3 gene fusion」の詳細全文を読む
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